Featured Articles

Why Bile Acids Are So Important in Non-Alcoholic Fatty Liver Disease (NAFLD) Progression

Non-alcoholic fatty liver disease (NAFLD) is a complex disease, affecting not just the liver, but also all other organs in the body. Despite an increasing amount of people worldwide developing NAFLD and having it progress to non-alcoholic steatohepatitis (NASH) and potentially cirrhosis, there is still no approved therapy. Therefore, huge efforts are being made to find and develop a successful treatment. One of the special interests is understanding the liver–gut axis and especially the role of bile acids in the progression of NAFLD. Farnesoid X receptor (FXR)-agonists have been approved und used in other liver diseases, such as primary biliary cholangitis (PBC) and primary sclerosing cholangitis (PSC), and have shown signs of being able to decrease inflammation and potentially steatosis. This review will mainly focus on targets/ligands that play an important role in bile acid metabolism and give an overview of ongoing clinical as well as pre-clinical trials. With the complexity of the issue, we did not aim at giving a complete review, rather highlighting important targets and potential treatments that could be approved for NAFLD/NASH treatment within the next few years.

The effects of multivitamins on cognitive performance: a systematic review and meta-analysis

Complementary medicine use is becoming increasingly popular with multivitamins being the most commonly used vitamin supplement. Although adequate vitamin and nutrient concentrations are necessary for optimal health and cognitive functioning, there is no scientific consensus as to whether multivitamin use prevents cognitive decline or improves mental functioning. The aim of the present study was to determine if multivitamins can be used efficaciously to improve cognitive abilities. A systematic review of randomized controlled trials was performed. Meta-analysis was performed on those cognitive tests used across the largest number of studies. Multiple electronic databases were searched until July 2011 by two authors. Randomized, placebo-controlled trials were considered appropriate if they reported on the chronic effects (≥1 month) of oral multivitamin supplementation on any valid cognitive outcomes. Ten trials were included in review (n = 3,200). Meta-analysis indicated that multivitamins were effective in improving immediate free recall memory (SMD = 0.32; 95% CI: 0.09-0.56, p < 0.01) but not delayed free recall memory (SMD = -0.14; 95% CI: -0.43-0.14, p = 0.33) or verbal fluency (SMD = 0.06; 95% CI: -0.05-0.18, p = 0.26). There was no evidence of publication bias or heterogeneity. Other cognitive abilities sensitive to AD pathology, such as executive and visuospatial functions, were found to be under researched. In conclusion, multivitamins were found to enhance immediate free recall memory but no other cognitive domains.

Systemic primary carnitine deficiency with hypoglycemic encephalopathy

Acute hypoglycemia in children is not an uncommon disease that can be encountered in the Emergency Department. Most cases of childhood hypoglycemia are caused by ketotic hypoglycemia due to missed meals. Often, hypoketotic hypoglycemia can also occur, which suggests hyperinsulinemia or a defect in fatty acid oxidation. Carnitine is essential for long chain fatty acids transfer into mitochondria for oxidation. We present a case of systemic primary carnitine deficiency who presented with seizures due to hypoketotic hypoglycemia.

Featured Videos

Solving Systemic Inflammation

Systemic Inflammation can toss any treatment plan into chaos. Clouding the bodies localized inflammation needed to rectify a problem.

Using Kapp-X can calm systemic inflammation allowing your body to properly process your NFkB responses. This means your patients can finally begin addressing the conditions causing their problems instead of the systemic inflammation clogging the internal pathways.

Dr. Brad Watts gives an in-depth 5 min look at how this exact problem arises and how you can confront it head on with the help of Kapp-X.

Fighting The Opioid Epidemic

Dr. Brad Watts discusses how practitioners can support patients battling Neuropathic Pain. With the Opioid epidemic on pace to cause over a half million deaths in the next decade finding ways to manage pain without addictive treatments have become a must for optimizing therapy. Dr. Watts covers why Opioids have taken such a commanding role in pain management. 

Get to the bottom of how to provide high-quality pain support without incorporating addictive treatments that cause more problems than they solve with this informative video. Learn how Biogenetix’ Pain Support Kit can play a key role in your patient’s treatment program. 

Escalate Regenerative Therapy

Dr. Brad Watts discusses how to get the most out of your patients’ Regenerative Therapy. Creating an optimal outcome for patients is the key to any therapy treatment. Dr. Watts covers the many points needed to establish an environment to support success. 

Help your patients achieve their desired results by managing & controlling inflammation through the entire process. Dr. Watts goes into detail about the myriad of ways you can address inflammation during therapy to ensure that treatments take hold. By following this path laid out, you can maximize your patients regenerative therapy from beginning to end.

Featured Webinars

Next Generation Neuro Support

Dr. Brad Watts hosts an enthralling webinar covering Next Generation Neuro Support. Learn about how the threat of Alzheimer’s & Cognitive Disorder have been wreaking havoc on the Baby Boomers. By looking at the lifestyle challenges facing patients, Dr. Watts covers what heightens the risks & how to reduce those risks even in patients deemed genetically prone.

Supporting Regenerative Pathways

Dr. Brad Watts has provided this informative webinar on supporting regenerative pathways and how to incorporate the Regenerative Kit into your patient’s treatment. This kit goes hand in hand with Regenerative Therapy programs. Learn about the role inflammation plays, the history behind the science for incorporating nutrition into recovery and how with the assistance of the Regenerative Kit you can enhance your patient experience.

Join the webinar below to find out what has everyone buzzing!

Integrating With Vitamin D

Listen to Dr. Brad Watts as he lays out the background information on Vit D therapeutic intervention, including who needs it, who gets it, and which formulations to use with which patients. This short 30 min webinar gives you the details you need and a plan to support your patients and family.

  • Of your bodies roughly 30,000 genes vitamin D affects 10% of them.
  • Vitamin D exhibits infection fighting abilities.
  • Low vitamin D levels are linked to increase risk of cognitive decline.

Vitamin D therapeutic intervention, is a great thing to learn about by joining the webinar below!



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